PLA-PEG纤维膜的制备及性能研究

Study on Preparation and Properties of PLA-PEG Nanofibrous Membranes

以丙交酯和聚乙二醇（分子量400）为原料,辛酸亚锡为催化剂,通过溶液聚合法制备了聚乳酸-聚乙二醇共聚物（PLA-PEG）。以三氯甲烷为溶剂,通过静电纺丝法制备了PLA-PEG纤维膜。采用傅里叶变换红外吸收光谱（FT-IR）、核磁共振氢谱（^1H-NMR）对制备的共聚物结构进行了表征,采用场发射扫描电镜（FE-SEM）、热重分析仪（TGA）、光学接触角测量仪分别对纤维膜的表面形貌、直径分布、热稳定性及亲水性进行测试,最后通过浸泡法测试了纤维膜的平衡吸水率。结果表明：成功合成了PLA-PEG共聚物;PLA-PEG纤维膜形貌规整,分布均匀,直径为500-1 500 nm;PLA-PEG降低了PLA的热分解温度,提高了材料的亲水性,当共聚物中PLA：PEG从100：0变化到91：9时,纤维膜的接触角从135.21°降至55.41°,材料的平衡吸水率提高到551.09%。

The PLA-PEG copolymer was prepared by solution polymerization using lactide and polyethylene glycol（molecular weight： 400） as raw materials and stannous octoate as catalyst. The PLA-PEG fiber membrane was prepared by electrospinning method using trichloromethane as the solvent. The structure of the copolymer was characterized by Fourier transform infrared absorption spectroscopy（FT-IR） and nuclear magnetic resonance（^1H-NMR）. The surface morphology, diameter distribution, thermal stability and hydrophilicity of the fiber membranes were measured by field emission scanning electron microscopy（FE-SEM）, thermogravimetric（TGA） and optical contact angle, respectively. Finally, the equilibrium water absorption was measured by soaking method. The results of FT-IR and 1 H-NMR showed that the PLA-PEG copolymer has been successfully synthesized in this experiment. Furthermore, FE-SEM result demonstrated that the morphology of the spun fiber is uniform.In addition, PEG can significantly improve the thermal stability of the material, and can also improve the hydrophilicity of the polylactic acid. the contact angle of the fiber membrane decreased from 135.21 ° to 55.41 ° when the ratio of PLA to PEG in the copolymer changed from 100：0 to 91：9, the balance of water absorption reached 551.09%, hydrophilic of the materials significantly improved and showing a good water absorption capacity.