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肠道菌群与多囊卵巢综合征的免疫学机制研究进展 被引量:16

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摘要 多囊卵巢综合征(PCOS)是育龄期女性常见的内分泌和代谢紊乱性疾病,是导致育龄女性月经失调和不孕的常见原因之一。PCOS的病因至今尚不完全清楚,近年来免疫因素及代谢异常成为PCOS的研究热点。肠道菌群作为人体不可或缺的"微生物器官",影响着宿主的营养代谢及免疫功能,在肥胖、胰岛素抵抗、桥本氏甲状腺炎等内分泌代谢疾病以及自身免疫疾病中有着十分重要的作用。本文拟从免疫学角度对肠道菌群参与PCOS的可能发病机制做一综述,以期为PCOS的治疗提供新的思路。
出处 《现代妇产科进展》 CSCD 北大核心 2018年第4期308-310,共3页 Progress in Obstetrics and Gynecology
基金 山东省重点研发计划项目(No:2017GSF19107) 山东省自然科学基金(No:ZR2017BH062) 国家自然科学基金(No:81102560)
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