昆虫精氨酸激酶研究进展

Advances in the research of arginine kinase in insects

精氨酸激酶是磷酸原激酶的一种,广泛分布于无脊椎动物组织内。在长期的进化过程中,不同昆虫精氨酸激酶在空间结构上出现了一定的分化,同时其氨基酸序列又具有高度的保守性。在功能上,精氨酸激酶主要参与能量代谢,而且可以维持昆虫和其他无脊椎动物正常的生命活动。此外,随着研究的深入,发现精氨酸激酶还具有参与自身免疫和麻痹寄主昆虫的作用。本文主要对昆虫精氨酸激酶的分布、结构和功能三个方面的研究进展予以综述。

As one kind of phosphagen kinases,arginine kinase is widely distributed in various tissues of invertebrates. In the long-term evolutionary process,the spatial structures of arginine kinases of different insects have differentiated. However,their amino acid sequences are highly conserved. Functionally,arginine kinases are primarily involved in energy metabolism and maintain the normal life activity in insects and other invertebrates. In addition,with the development of modern scientific techniques,more and more studies show that arginine kinase also plays an important role in autoimmunity and paralysis of host insects. In this article,the distribution,structure and functions of arginine kinases in insects were reviewed.