窝儿七中1个新的木脂素成分

A new lignan from radix and rhizome of Diphylleia sinensis

目的研究窝儿七(中华山荷叶Diphylleia sinensis的根及根茎)的化学成分。方法采用硅胶、葡聚糖凝胶Sephadex LH-20、高效液相等色谱技术进行分离纯化,根据理化性质和波谱方法进行结构鉴定。结果从窝儿七根茎95%乙醇提取物中分离得到3个化合物,分别鉴定为山荷叶素-4-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖苷(1)、爵床脂素A(2)、(+)-tanegool-7′-methylether(3)。结论化合物1为新化合物,命名为爵床苷G;化合2和3为首次从山荷叶属植物中分离得到。

Objective To study the chemical constituents from the radix and rhizome of Diphylleia sinensis. Methods Silica gel column chromatography, Sephadex LH-20, high performance liquid chromatography, and other chromatographic techniques were used for separation and purification. The structures were elucidated by physical and chemical methods and spectral data. Results Three compounds were isolated from the 95% ethanol extract in the rhizome of D. sinensis, and their structures identified as diphyllin-4-O-β-D-glucopyranosyl-（1→6）-β-D-glucopyranoside（1）, justicdin A（2）, and（＋）-tanegool-7′-methylether（3）. Conclusion Compound 1 is a new compound named procumbenoside G; Compounds 2 and 3 were isolated from the Diphylleia for the first time.