地屈孕酮与黄体酮治疗先兆流产的效果比较

The effect of threatened abortion on dydrogesterone and progesterone treatment

目的观察比较先兆流产患者应用地屈孕酮与黄体酮治疗的临床效果。方法从医院接受先兆流产治疗的患者中随机选取148例作为研究对象,并依据就诊顺序分为观察组和对照组,每组74例。对照组予以黄体酮治疗,观察组接受地屈孕酮治疗。观察2组治疗前后人绒膜促性腺激素及血清孕酮水平变化,症状缓解时间、症状消失时间、治疗时间及保胎成功率。结果治疗后,2组人绒膜促性腺激素及血清孕酮水平较治疗前均改善,且观察组改善情况优于对照组(P均<0.01);观察组症状缓解时间、症状消失时间及治疗时间均短于对照组(P<0.01);观察组保胎成功率为93.24%,高于对照组的82.43%(P<0.05)。结论先兆流产患者应用地屈孕酮治疗可获取更高的保胎成功率。

Objective To observe the clinical effect of dydrogesterone and progesterone treatment in patients with threatened abortion. Methods A total of 148 patients who received threatened abortion treatment from a hospital were randomly selected as the subject of this study,and were divided into an observation group and a control group according to the order of visits,with 74 cases in each group. The control group was treated with progesterone,and the observation group was treated with dydrogesterone. The changes of human chorionic gonadotropin and serum progesterone before and after treatment in the two groups were observed,as well as the time of symptom relief,the time of disappearance of symptoms,treatment time,and the success rate of fetal loss. Results After treatment,the levels of human chorionic gonadotropin and serum progesterone in both groups were improved compared with those before treatment,and the improvement in the observation group was better than that in the control group（ P 〈0. 01）; the symptom relief time and the disappearance time of symptoms in the observation group and The treatment time was shorter than that in the control group（ P 〈0. 01）; the success rate of the fetus in the observation group was 93. 24%,which was higher than that of the control group 82. 43%（ P〈 0. 05）. Conclusion The use of dydrogesterone in patients with threatened abortion can achieve higher success rates.