上海市某郊区社区人群幽门螺杆菌感染的流行病学调查

Epidemiological survey on Helicobacter pylori infection among Shanghai suburb residents

【目的】了解上海市某郊县体检人群开展幽门螺杆菌(Helicobacter pylori,Hp)感染流行现况。【方法】于2016年9~12月份,共调查3 258例参加体检的40岁及以上居民,利用免疫胶体金法对上述人群进行Hp感染的血清学筛查,并开展问卷调查,估计当地居民的Hp感染率。【结果】该郊县调查人群Hp总感染率为28.0%(95%CI:26.5%~29.5%)。其中,男性为31.5%(95%CI:29.1%~33.9%),女性为25.2%(95%CI:23.2%~27.2%);年龄70岁及以上人群的Hp感染率最低,为24.1%(95%CI:20.9%~27.2%);吸烟者Hp感染率为35.4%(95%CI:32.2~38.7),非吸烟者为25.3%(95%CI:23.6~27.1);饮酒者Hp感染率为32.3%(95%CI:28.9~35.7),非饮酒者为27.0%(95%CI:25.3~28.8)。不同性别、不同年龄、吸烟者与非吸烟者、饮酒者与非饮酒者的Hp感染率差异均有统计学意义。【结论】本次调查郊县人群的Hp总感染率略低于其他地区,男性、吸烟、饮酒及年龄50岁以下人群的Hp感染率较高。

[Objective] To investigate Helicobacter pylori infection situation in Shanghai suburb residents through epidemiological survey. [Methods] Aged 40 or above 3 258 participants receiving physical examination were selected between Sep. 2016 and Dec. 2016. Serological analyzed blood samples by dot immunochromatographic assay and a questionnaire survey were conducted. [Results]The infection rate in Shanghai suburb residents was 28. 0%（ 95% CI： 26. 5%-29. 5%）. The male rate was 31. 5%（ 95% CI： 29. 1%-33. 9%） and the female rate 25. 2%（ 95% CI： 23. 2%-27. 2%）,which had significant difference. The lowest infection rate was 24. 1%（ 95% CI： 20. 9%-27. 2%） in the age group of older than 70 years old with significant differences among various age. The infection rates of smokers and non-smokers were 35. 4%（ 95%CI： 32. 2-38. 7） and 25. 3%（ 95%CI： 23. 6-27. 1） respectively. The infection rates of drinkers and non-drinkers were 32. 3%（ 95% CI： 28. 9-35. 7） and 27. 0%（ 95% CI： 25. 3-28. 8） respectively. The differences were all significant above. [Conclusion] The infection rate of H. pylori in Shanghai suburb residents is related with sex,age,smoke and alcohol.