摘要
抗苗勒管激素(AMH)是转化生长因子β超家族成员之一,在雌性动物卵巢颗粒细胞中表达,通过自分泌或旁分泌作用调控卵泡发育及卵母细胞的成熟,并作为有效的内分泌标记物用于预测牛超数排卵效率及体外胚胎产量。本文综述了AMH的表达模式、转导途径、生理功能,以及其在不同雌性动物中的研究进展,为促进其在动物繁殖领域中的深入研究与应用提供参考。
Anti-Mullerianhormone（AMH） is one of the members of the transforming growth factor beta superfamily, expressed in ovarian granulosa cells of female animals, and regulate follicular development and oocyte maturation through autocrine or paracrine. It＇s also an effective endocrine marker to predict ovulation efficiency and embryo production in vitro.This study reviews the expression patterns, transduction pathways, physiological functions, and application researches in different female animals of AMH, in order to promote its research and application in the field of animal reproduction.
作者
李赞
乔同
姜婷婷
牛凯峰
王贵强
秦则平
杨利国
梁爱心
LI Zan;QIAO Tong;JIANG Ting-ting;NIU Kai-feng;WANG Gui-qiang;QIN Ze-ping;YANG Li-guo;LIANG Ai-xin(Key Laboratory of Agricultural Animal Gentics,Breeding and Reproduction,Ministry of Education,Huazhong Agricultural University, Wuhan 430070;Livestock Breeding Center of Hubei Province, Wuhan 430070)
出处
《中国奶牛》
2018年第4期24-27,共4页
China Dairy Cattle
基金
中央高校基本科研业务费专项基金(2662016PY120)
国家自然科学基金(31402078)
