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阿尔茨海默病的靶向治疗策略

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摘要 阿尔茨海默病(Alzheimer disease,AD)是一种老年人易发且常见的痴呆类型,其发病机制与脑中AB异常累积形成老年斑块及Tau过度磷酸化形成神经纤维缠结有关。因此,Aβ及Tau蛋白是目前开发AD治疗药物的两大主要靶点。本文将对基于这两大靶点的AD治疗策略作一综述。
作者 卢齐伟
出处 《南通大学学报(医学版)》 2018年第2期128-130,共3页 Journal of Nantong University(Medical sciences)
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