肝脏疾病诊断中采取血清ALT、AST、GGT检测的临床应用

Clinical Application of Serum ALT,AST,GGT Detection in Liver Disease Diagnosis

目的:对肝脏疾病诊断中采取血清ALT(丙氨酸氨基转移酶)、AST(天门冬氨酸氨基转移酶)、GGT(谷氨酰基转移酶)检测的临床应用进行研究分析。方法:选取笔者所在医院接诊的肝脏疾病病患130例为试验组,另选择80例在笔者所在医院行健康体检的健康人员为对照组。使用全自动分化仪检测两组人员的血清ALT、AST、GGT水平和阳性体现状况,分析对照组与各类型肝脏疾病病患血清ALT、AST、GGT水平变化和阳性体现状况。结果:试验组病患的血清ALT、AST、GGT水平明显高于对照组,差异有统计学意义(P<0.05);并且试验组病患不同类型肝脏疾病间的血清水平比较差异有统计学意义(P<0.05);在阳性体现状况中试验组病患ALT阳性率分别为慢性病毒性肝炎94.83%、肝硬化39.13%、肝癌26.92%;AST阳性率分别为慢性病毒性肝炎89.66%、肝硬化86.96%、肝癌84.62%;GGT阳性率分别为肝癌76.92%、56.9%、肝硬化63.04%、慢性病毒性肝炎56.9%。结论:在肝脏疾病诊断中血清ALT、AST、GGT水平检测有着重要的作用,其为肝脏疾病诊断提供了更为科学的辨别依据,有着较高的临床推广应用价值。

Objective：To analyze of the serum ALT（alanine aminotransferase）,AST（aspartate aminotransferase）,GGT（glutamyl transferase） in the diagnosis of liver disease.Method：130 patients with liver diseases in our hospital were selected as the experimental group,and 80 healthy persons who underwent physical examination in our hospital as the control group.The serum levels of ALT,AST,GGT and positive expression of two groups of patients were detected by automatic differentiation instrument,and the changes of serum ALT,AST,GGT levels and positive expression status were analyzed in control group and various types of liver diseases.Result：The experimental group patients serum ALT,AST and GGT levels were significantly higher than the control group,the differences were significant（P〈0.05）,and the experimental group had serum level of comparison between different types of liver disease also had statistical significance（P〈0.05）,in the experimental group positive rate reflects the status of patients with ALT respectively were chronic viral hepatitis,liver cirrhosis,liver cancer,they were 94.83%,39.13%,26.92% respectively,the positive rate of AST of chronic viral hepatitis,liver cirrhosis,liver cancer were 89.66%,86.96%,84.62%,the positive rate of GGT of chronic viral hepatitis,liver cirrhosis,liver cancer were 56.9%,63.04%,76.92%.Conclusion：The detection of serum ALT,AST and GGT levels play an important role in the diagnosis of liver diseases,which provides a more scientific basis for the diagnosis of liver diseases,and has high clinical application value.