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无创DNA检测临床应用的研究进展 被引量:1

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摘要 无创DNA检测是通过母体外周血血浆中提取胎儿游离DNA,对胎儿遗传信息进行分析的检测方式,常应用于胎儿染色体非整倍体等疾病进行筛查,具备高敏感性、特异性等优点,在产前诊断中广泛应用。本文将对其最新研究进展进行综述。
出处 《实用妇科内分泌电子杂志》 2017年第30期22-23,共2页 Electronic Journal of Practical Gynecological Endocrinology
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  • 1Walknowska J, FA Conte, MM Grumbach. Practical and theoretical implications of fetal-maternal lymphocyte transfer[J].Lancet, 1969, 1 (7606) :1119-22.
  • 2Chen XQ, et al. Microsatellite alterations in plasma DNA of small cell lung cancer patients[J].Nat Med, 1996,2 (9) : 1033-5.
  • 3Lo YM, et al. Presence of fetal DNA in maternal plasma and serum[J].Lancet, 1997, 350 (9076) :485-7.
  • 4Held CA, et al. Real time quantitative PCR[J].Genome Res, 1996,6 (10) :986-94.
  • 5Lo YM, et al. Quantitative analysis of fetal DNA in maternal plasma and serum :implications for noninvasive prenatal diagnosis[J].Am J Hum Genet, 1998,62 (4) :768-75.
  • 6Wang E, et al. Gestational age and maternal weight effects on fetal cell-free DNA in maternal plasma[J].Prenat Diagn, 2013, 33 (7) : 662-6.
  • 7ILo YM, et al. Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus[J].Sci Transl Med,2010,2 (61) :61ra91.
  • 8Hui L, JI Vaughan, M Nelson. Effect of labor on postpartum clearance of cell-free fetal DNA from the maternal circulation[J]. Prenat Diagn, 2008,28 (4) :304-8.
  • 9Bianchi DW. Circulating fetal DNA :its origin and diagnostic potential-a review[J].Placenta, 2004, 25 Suppl A :$93-S101.
  • 10Sequencing-based tests to determine fetal down syndrome (trisomy 21 ) from maternal plasma DNA[J].Technol Eval Cent Assess Program Exec Summ, 2013,27 ( 10 ) .-1-6.

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