黄酮类化合物与其他化合物相互作用的研究进展

Advances in Understanding the Interaction between Flavonoids and Other Compounds

黄酮类化合物是一类广泛存在于植物根、茎、叶、花和果实中的次生代谢有机物,其结构复杂,种类繁多,因其对人类健康有很强的积极作用,如抗癌、抗菌、抗病毒、抗炎症、抗过敏等而备受关注,人们通过体内、体外实验验证了其多种生物活性。然而黄酮类化合物通常与其他种类化合物如碳水化合物、蛋白质、脂质、酸等在植物体内共存,与它们一起摄入人体内并且可以与其他化合物相互影响或者结合,因此黄酮类化合物的功能与其他化合物有着密不可分的联系。本文综述了黄酮类化合物与其他化合物之间的相互作用,并阐述了其作用机制与结果。

Flavonoids are a wide variety of secondary plant metabolites with complex structures that widely exist in plant roots, stems, leaves, fiowers and fruits. These compounds have attracted much attention due to their greatly positive effects on human health, such as anticancer, antibacterial, anti-viral, anti-infiammatory and anti-allergic. Researchers have verified their various biological activities in vivo and in vitro. However, fiavonoids usually coexist with other compounds in plants, such as carbohydrate, protein, lipid and acid, and interact with these compounds inside the body when ingested together. Therefore, the functions of fiavonoids have a close relationship with other compounds. The interaction between fiavonoids and other compounds together with the underlying mechanisms and the outcome is reviewed in this paper.