单侧额下入路显微外科手术治疗大型嗅沟脑膜瘤16例分析

Study on microsurgical treatment by unilateral subfrontal approach in 16 patients with large olfactory groove meningiomas

目的探讨经单侧额下入路显微外科技术切除大型嗅沟脑膜瘤的方法及治疗效果。方法回顾性分析2010年1月至2017年12月利用显微外科技术切除16例大型嗅沟脑膜瘤患者的临床资料。结果肿瘤全部切除（Simpson Ⅰ和Ⅱ级）14例，次全切除（Simpson Ⅲ级）2例，无手术死亡病例；术后随访疗效满意，无复发。结论经单侧额下入路显微外科技术治疗大型嗅沟脑膜瘤符合微侵袭的治疗理念，能够提供足够的操作空间，可以取得令人满意的治疗效果，是一种值得优先考虑的手术方式。

Objective To study the method and therapeutic effect of microsurgical treatment by unilateral subfrontal approach in patients with large olfactory groove meningiomas. Methods The clinical data of 16 patients with large olfactory groove meningiomas who had underwent microsurgical treatment by unilateral subfrontal approach from January 2010 to December 2017 were analyzed retrospectively. Results Total removal of tumor （Simpson Ⅰ and Ⅱ grade） was achieved in 14 cases and subtotal removal of the tumor （Simpson Ⅲ） was in 2 cases. No patient died from the microsurgery. The treatment effect was satisfactory in all patients during the follow-up. Conclusions The microsurgical treatment by unilateral subfrontal approach in patients with large olfactory groove meningiomas conforms to the concept of minimal invasive surgery, which provides enough surgical space, and the effect of surgery is satisfactory. So the approach is a good choice for the removal of large olfactory groove meningiomas.