探讨序贯神经阻滞治疗恶性肿瘤放化疗并发带状疱疹的临床疗效

Investigation on clinical efficacy of sequential nerve block in the treatment of malignant tumor with radiotherapy and chemotherapy complicated with herpes zoster

目的探讨序贯神经阻滞治疗恶性肿瘤放化疗并发带状疱疹的临床疗效。方法 46例恶性肿瘤放化疗并发带状疱疹患者,随机分为观察组和对照组,各23例。对照组采用常规治疗方法 ,观察组在对照组基础上采用序贯神经阻滞治疗,比较两组患者止疱、结痂、脱痂、疼痛缓解时间及治愈情况和遗留神经痛情况。结果观察组止疱、结痂、脱痂、疼痛缓解时间均短于对照组,差异有统计学意义(P<0.05)。观察组治愈率86.67%明显高于对照组的63.33%,遗留神经痛发生率6.67%明显低于对照组的33.33%,差异有统计学意义(P<0.05)。结论采用序贯神经阻滞治疗恶性肿瘤放化疗并发带状疱疹能够达到较好的临床效果,临床应早发现、早治疗,以提升治愈率,提高患者生存质量。

Objective To discuss the clinical efficacy of sequential nerve block in the treatment of malignant tumor with radiotherapy and chemotherapy complicated with herpes zoster. Methods A total of 46 patients with malignant tumor with radiotherapy and chemotherapy complicated with herpes zoster were randomly divided into observation group and control group, with 23 cases in each group. The control group received conventional therapy, and the observation group received sequential nerve block on the basis of the control group. Comparison were made on herpes stopping, scarring and dislocation time, pain relief time, healing and residual neuralgia between the two groups. Results The observation group had shorter herpes stopping, scarring and dislocation time, pain relief time than the control group, and the difference was statistically significant（P〈0.05）. The observation group had obviously higher healing rate as 86.67% than 63.33% in the control group, and obviously lower prevalence of residual neuralgia as 6.67% than 33.33% in the control group. Their difference was statistically significant（P〈0.05）. Conclusion Sequential nerve block for the treatment of malignant tumor with radiotherapy and chemotherapy complicated with herpes zoster can achieve better clinical effect. Early detection and early treatment can improve the healing rate and improve the quality of life of patients.