一例产超广谱β-内酰胺酶大肠埃希菌血流感染的药学实践

Pharmaceutical practice of one case of bloodstream infection with extended spectrum β-lactamase producing Escherichia coli

目的通过临床药师参与抗感染药物治疗的成功药学实践,探讨临床药师在药物治疗中发挥的作用。方法临床药师通过参与1例医院获得性产超广谱β-内酰胺酶(ESBLs)大肠埃希菌血流感染患者的会诊与全程治疗,对抗感染的治疗方案进行分析的同时提出优化建议,并对患者进行用药监护。结果医师采纳临床药师提出的治疗建议。治疗后,患者体温及感染指标恢复正常,血培养结果转阴,感染得到有效控制。结论临床药师立足临床,通过积极参与患者的药物治疗实践,为患者提供药学监护,可提高药物治疗的安全性和有效性。

Objective To probe the role of clinical pharmacists in the pharmaceutical therapy through successful pharmaceutical practice of their participation in anti-infective treatment. Methods The clinical pharmacists participated in consultation and the whole treatment process of one patient who suffered from bloodstream infection treated with extended spectrum β-lactamase producing Escherichia coli,and the infection therapy program was analyzed and optimization recommendations were proposed,then the pharmaceutical care was implemented by clinical pharmacists. Results The physicians adopted the treatment advice provided by the clinical pharmacists,and the body temperature and infection signs of the patient recovered to normal and blood culture results turned negative,the infection being controlled effectively. Conclusion Based on clinical practice,the clinical pharmacists take part in the patients＇ pharmaceutical treatment practice actively and provide the necessary pharmaceutical care for patients,which can improve the safety and efficacy of drug treatment.