阿司匹林与比索洛尔联合用药对冠心病经皮冠状动脉介入术后患者心脏康复的影响

Effect of aspirin combined with bisoprolol on cardiac rehabilitation in patients with coronary heart diseaseafter percutaneous coronary intervention

目的对冠心病经皮冠状动脉介入术后患者采用阿司匹林联合比索洛尔进行治疗,探究该治疗方案对患者心脏康复功能的影响.方法选取本院收治的63例冠心病患者作为研究对象,并将其随机分为观察组（32例）与对照组（31例）,所有患者均进行经皮冠状动脉介入术治疗,术后给予观察组患者阿司匹林联合比索洛尔治疗,对照组则单独采用阿司匹林进行治疗,对两组患者的心脏康复情况进行观察、比较.结果经不同方案治疗后,在左室舒张末期内径（LVEDD）、左室收缩末期内径（LVESD）、左室射血分数（LVEF）等心脏功能指标的比较上,观察组患者的各项心脏功能指标均优于对照组,差异有统计学意义（P〈0.05）;在舒张功能的比较上,观察组患者中正常舒张功能所占比例为68.75%,明显高于对照组的41.94%,差异有统计学意义（P〈0.05）.结论对冠心病经皮冠状动脉介入术后患者采用阿司匹林联合比索洛尔治疗,可有效改善患者的心脏功能,促进其心脏康复,值得推广.

Objective To investigate the effect of aspirin combined with bisoprolol on cardiac rehabilitation in patients with coronary heart disease after percutaneous coronary intervention. Methods Sixty-three patients with coronary heart disease admitted to our hospital were selected as study subjects and were randomly divided into observation group （32 cases） and control group （31 cases）. All patients underwent percutaneous coronary intervention, and the observation group was treated with aspirin combined with bisoprolol after surgery, while the control group was treated with aspirin alone. The cardiac rehabilitation of the two groups were observed and compared. Results After treatment with different regimens, the cardiac functional parameters [left ventricular end-diastolic diameter （LVEDD）, left ventricular end-systolic diameter （LVESD）, and left ventricular ejection fraction （LVEF）] of the patients in the observation group were better than those in the control group （P〈0.05）. The ratio of normal diastolic function in the observation group was 68.75%, signifcantly higher than that in the control group （41.94%） （P〈0.05）. Conclusion Aspirin combined with bisoprolol can effectively improve the cardiac function of patients with coronary heart disease after percutaneous coronary intervention, and promote their cardiac rehabilitation, which is worth promoting.