纳米脂肪联合结构脂肪移植在眶周年轻化中的疗效观察

Clinical efficacy of combined nano-fat and structural fat transplantation for periocular rejuvenation

目的探讨联合应用纳米脂肪和结构脂肪移植在改善眶周软组织容积缺失、暗沉及细纹的应用研究。方法选取大腿作为脂肪供区，采用Coleman的结构脂肪移植技术获取结构脂肪，Tonnard的纳米脂肪技术获取纳米脂肪，将得到的结构脂肪在眶周凹陷处多层次、多隧道、少量均匀地注射，同时将得到的纳米脂肪均匀注射在眶周细纹及暗沉部位的真皮及皮下层内。结果共治疗48例患者，术后随访3-12个月，平均随访6个月，42例患者在1次注射填充后即达到满意效果，无一例出现感染、脂肪液化、脂肪坏死及脂肪栓塞等并发症。2例患者不满意，因上睑脂肪堆积，感觉上睑臃肿；4例患者基本满意，黑眼圈改善不明显。结论联合纳米脂肪及结构脂肪移植可以有效地填充眶周凹陷，并且同时改善暗沉，达到年轻化的满意效果。

Objective To investigate the clinical efficacy of combined nano-fat and structural fat transplantation for periocular rejuvenation, such as fine wrinkle, darkness and volume loss. Methods Structural fat was harvested by Coleman＇s structural fat grafting technique from thigh and was grafted at different layers for depression correction. Nano-fat was harvested by Tonnard＇s nano-fat technology from thigh and was injected smoothly intradermally and subcutaneously for correction of fine wrinkle and darkness. Results The patients were followed up for 3--12 months, 6 months in average. Satisfactory result was achieved in 42 cases after only one operation. No complication happened. 2 cases was unsatisfied due to upper eyelid fullness. 4 cases didn＇t get improvement in periocular darkness. Conclusions Combined nano-fat and structural fat transplantation are effective for periocular rejuvenation, including depression deformity and skin darkness.