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罗哌卡因局部镇痛联合曲马多口服对行腹腔镜阑尾切除患者术后镇痛的效果 被引量:2

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摘要 【目的】观察罗哌卡因局部镇痛联合曲马多口服对腹腔镜阑尾切除术(LA)患者术后镇痛的效果。【方法】本院行LA患者80例,随机分为观察组和对照组。两组患者手术结束后,均在缝合切口前以0.5%罗哌卡因10 mL喷洒切口内部,再以0.5%罗哌卡因3 mL局部浸润切口。观察组患者术后6 h开始口服曲马多50 mg,每12 h给予50 mg。对照组患者在相同时间给予相同外观、质量的淀粉片作为安慰剂。采用视觉模拟评分(VAS)法比较两组术后8 h、12 h、24 h、36 h、48 h患者疼痛情况。【结果】术后6 h,两组患者VAS评分比较差异无显著性(P〉0.05);术后12 h、24 h、36 h、48 h,观察组VAS评分明显低于对照组(均P〈0.05)。术后观察组患者的下床时间和排气时间早于对照组(均P〈0.05);两组患者均无呼吸抑制的情况发生,对照组眩晕和恶心呕吐发生率高于观察组(均P〈0.05)。术后对照组2例患者要求追加止痛药,观察组无此现象。【结论】罗哌卡因局部镇痛联合曲马多口服对行LA患者术后镇痛效果显著,且安全有效。
出处 《医学临床研究》 CAS 2018年第4期785-786,共2页 Journal of Clinical Research
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