莫沙必利与多潘立酮治疗功能性消化不良的临床疗效比较

Clinical Curative Effect Comparison of Mosapride and Domperidone in Treatment of Functional Dyspepsia

目的比较莫沙必利与多潘立酮治疗功能性消化不良的临床疗效。方法选用100例患有功能性消化不良的患者根据实验随机性原则进行分组,对照组50例患者采用多潘立酮治疗,研究组50例患者采用莫沙必利治疗,对比经过两种不同药物治疗后患者的治疗效果、疾病复发率以及服药后不良反应情况。结果研究组的治疗有效率为96%,对照组的治疗有效率为94%,组间对比差异不具有统计学意义(P>0.05);在不良反应情况、疾病复发率上,研究组小于对照组,组间对比,差异具有统计学意义(P<0.05)。结论莫沙必利治疗功能性消化不良的临床效果优异,具有一定的临床应用意义。

Objective To compare clinical effect of mosapride and domperidone in treatment of functional dyspepsia. MethodsChoose 100 cases functional dyspepsia patients, divide them into groups based on random principle of experiment. 50 cases in control group were treated with domperidone, and 50 in study group with mosapride. Compare treatment effect, recurrence rate, medication adverse reactions after treatment of two different medicine. Results Effective rate of treatment group was 96%, that of control group was 94%, difference showed no statistical significance（P〉0.05）; adverse reaction, recurrence rate of study group was less than control group, comparison difference showed statistical significance between two groups,（P〈0.05）. Conclusion Mosapride has good clinical effect in treatment of functional dyspepsia with some certain clinical application significance.