老龄化对内源性注意的影响研究

Research of the Aging Effects on Endogenous Attention

目的:观察老年人和年轻人的内源性注意行为学及事件相关电位(ERP)表现,探讨老龄化对内源性注意的影响及其机制。方法:参考Posner的经典的"cue-target"范式设计内源性注意任务,分别记录和分析年轻人和老年人行为学和事件相关电位波形P1、N1,比较老年人和年轻人在内源性注意任务中的不同表现。结果:在内源性注意条件下,年轻人的反应时明显短于老年人(P<0.05),对于N1成分的波幅,年龄主效应显著(P<0.05),年轻人较老年人诱发更大的N1波幅。对于N1成分的潜伏期,年龄主效应显著(P<0.05),年轻人潜伏期明显短于老年人。结论:老龄化对内源性注意的早期阶段有影响,在提高老年人注意力时应当对注意的不同类型进行评估和分类以采取合适的治疗策略。

Objective： To observe the behavioral performance and the waves in ERP in endogenous attention, and discuss the aging effect on endogenous attention and the mechanisms. Methods： Posner＇s cue-target paradigm combined with ERP was used to study the effect of aging on the endogenous attention, the early stage ERP components P1 and N1 were recorded and analyzed. Results： In the endogenous attention task, the response time of younger subjects was shorter than that of the older subjects （P〈0.05）, for the component N 1, the amplitude of younger subjects was larger than that of the older subjects（P 〈 0.05）, and the latency of younger subjects was shorter than that of the older subjects（P〈0.05）. Conclusions： Aging affected the endogenous attention from the early stage of attention.