期刊文献+

Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study 被引量:1

Childhood glaucoma profile in Dakahelia, Egypt: a retrospective study
下载PDF
导出
摘要 AIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network(CGRN) classification retrospectively to evaluate its convenience.METHODS: A retrospective study in which the medical files of all glaucoma patients 〈16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed. Collected data included: age, gender, laterality, visual acuity(VA), refraction, intraocular pressure(IOP), corneal diameter, cup-disc ratio, types and number of surgeries and antiglaucomatous drugs(AGD) at the first and last visit. Prevalence of different subtypes was calculated and means of clinical features were compared.RESULTS: A total of 305 eyes of 207 patients were included classified into 6 groups: primary congenital glaucoma(PCG), juvenile open angle glaucoma(JOAG), glaucoma associated with systemic disease, glaucoma associated with ocular anomalies, acquired glaucoma and glaucoma following cataract surgery. PCG was the predominant type(55.1%) followed by acquired glaucoma(29.5%). Males represented 63.8% of the whole studied patients. Glaucoma associated with ocular anomaly group showed the youngest age at diagnosis(21.9±30.0 mo). The shortest corneal diameter was recorded in post cataract group(10.4±0.5 mm). Highest cup-disc ratio was found in the PCG group(P〈0.0005). Glaucoma associated with systemic disease presented with the highest baseline IOP(34.5±5.0 mm Hg). All the cases with PCG were treated surgically with 21.8% required more than one surgery. The majority of the patients(74.2%) in the acquired group were treated medically. Combined trabeculotomy-trabeculectomy was the most frequent operation done, accounting for 34.5% of all primary surgeries. Ahmed valve implantation comprised 87% of the secondary surgeries. Acquired glaucoma group had the highest percent of eyes with good final Snellen's VA(69.4%), while glaucoma associated with ocular anomaly group had poorest final VA. CONCLUSION: PCG is the most prevalent type of childhood glaucoma, followed by acquired glaucoma especially traumatic hyphema. Combined trabeculotomytrabeculectomy and Ahmed valve implantation are the most common surgical interventions. CGRN classification is found to provide a consensus skeleton and is recommended to be integrated in our routine ongoing clinical practice. AIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network(CGRN) classification retrospectively to evaluate its convenience.METHODS: A retrospective study in which the medical files of all glaucoma patients 〈16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed. Collected data included: age, gender, laterality, visual acuity(VA), refraction, intraocular pressure(IOP), corneal diameter, cup-disc ratio, types and number of surgeries and antiglaucomatous drugs(AGD) at the first and last visit. Prevalence of different subtypes was calculated and means of clinical features were compared.RESULTS: A total of 305 eyes of 207 patients were included classified into 6 groups: primary congenital glaucoma(PCG), juvenile open angle glaucoma(JOAG), glaucoma associated with systemic disease, glaucoma associated with ocular anomalies, acquired glaucoma and glaucoma following cataract surgery. PCG was the predominant type(55.1%) followed by acquired glaucoma(29.5%). Males represented 63.8% of the whole studied patients. Glaucoma associated with ocular anomaly group showed the youngest age at diagnosis(21.9±30.0 mo). The shortest corneal diameter was recorded in post cataract group(10.4±0.5 mm). Highest cup-disc ratio was found in the PCG group(P〈0.0005). Glaucoma associated with systemic disease presented with the highest baseline IOP(34.5±5.0 mm Hg). All the cases with PCG were treated surgically with 21.8% required more than one surgery. The majority of the patients(74.2%) in the acquired group were treated medically. Combined trabeculotomy-trabeculectomy was the most frequent operation done, accounting for 34.5% of all primary surgeries. Ahmed valve implantation comprised 87% of the secondary surgeries. Acquired glaucoma group had the highest percent of eyes with good final Snellen's VA(69.4%), while glaucoma associated with ocular anomaly group had poorest final VA. CONCLUSION: PCG is the most prevalent type of childhood glaucoma, followed by acquired glaucoma especially traumatic hyphema. Combined trabeculotomytrabeculectomy and Ahmed valve implantation are the most common surgical interventions. CGRN classification is found to provide a consensus skeleton and is recommended to be integrated in our routine ongoing clinical practice.
出处 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第4期674-680,共7页 国际眼科杂志(英文版)
关键词 childhood glaucoma classification Egypt epidemiology childhood glaucoma classification Egypt epidemiology
  • 相关文献

参考文献1

二级参考文献30

  • 1Beck AD.Diagnosis and management of pediatric glaucoma.Ophthalmol Clin North Am 2001; 14:501-512.
  • 2Ho CL,Walton DS.Primary congenital glaucoma:2004update.J Pediatr Ophthalmol Strabismus 2004; 41:271-288.
  • 3Taylor RH,Ainsworth JR,Evans AR,Levin AV.The epidemiology of pediatric glaucoma:the Toronto experience.J AAPOS 1999; 3:308-315.
  • 4Gao DW,Kubota T,Suglno K,Sugai S,Inomata H.A statistical comparison study of glaucoma in the Third Affiliated Hospital of China Medical College and Kyushu University.Nippon Ganka Gakkai Zasshi 1989; 93:458-465.
  • 5Dandona L,Williams JD,Williams BC,Rao GN.Population-based assessment of childhood blindness in southern India.Arch Ophthalmol 1998; 116:545-546.
  • 6Bejjaui BA,Stockton DW,Lewis RA,Tomey KF,Ducker DK,Jabak M,et al.Multiple CYP1B1 mutations and incomplete penetrance in an inbred population segregating primary congenital glaucoma suggest frequent de novo events and a dominant modifier locus.Hum Mol Genet 2000; 9:367-374.
  • 7Gencik A.Epidemiology and genetics of primary congenital glaucoma in Slovakia.Description of a form of primary congenital glaucoma in gypsies with autosomal-recessive inheritance and complete penetrance.Dev Ophthalmol 1989;16:76-115.
  • 8Kipp MA.Childhood glaucoma.Pediatr Clin North Am 2003;50:89-104.
  • 9Franks W,Taylor D.Congenital glaucoma--a preventable cause of blindness.Arch Dis Child 1989; 64:649-650.
  • 10Shaffer RN.Genetics and the congenital glaucomas.Am J Ophthalmol 1965; 60:981-994.

共引文献11

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部