一种用于侧脑室模拟穿刺模型的研制与应用

Manufacturing and Application of a Solid Model for Ventricular Puncture Surgical Simulation

本研究基于颅脑CT、MRI影像数据,利用3D打印技术制作患者的颅脑实体模型,应用于模拟侧脑室穿刺手术。由CT、MRI分别提供头皮、颅骨、血管及侧脑室、脑组织等影像数据,通过Mimics软件重建获得各组织结构数字模型。利用3D打印技术制作颅脑主体、中空的侧脑室嵌件以及脑组织模具,并使用水凝胶进行脑组织倒模,制作高度逼真的患者颅脑实体模型。最后通过医生进行模拟侧脑室穿刺手术,验证在该实体模型上进行手术训练的可行性。利用上述方法制作的颅脑实体模型可直观显示人脑主要结构,通过注入液体可使侧脑室内部达到一定压力,模拟患者的颅内压环境,经侧脑室模拟穿刺,术者的操作感受与实际手术近乎一致。3D打印制作的颅脑实体模型可应用于临床的培训、教学以及考核方面。

Based on brain CT and MRI image data, this study used 3D printing technology to produce patients’ brain entity model, which was applied to simulate lateral ventricle puncture operation. Data of scalp, skull, vessel, ventricular and brain tissue were obtained by CT and MRI scan, and digital models of each were reconstructed by Mimics software. Using 3D printing techniques, the model of a more realistic nature could be created, which contained the main part of the brain, the hollow lateral ventricles and brain tissues made by hydrogel, mimicking real brain tissue. Finally, the operation of the simulated lateral ventricle puncture was carried out to validate the feasibility of the surgical training on the model. The brain model could visually display the main structure of human brain tissue. By injecting liquid, the ventricular could achieve a certain amount of pressure which could simulate the real intracranial pressure environment of the patient. The sensation of simulation was almost the same as that of the actual operation. The 3D printed brain solid model can be used for clinical training, teaching and assessment.