舒芬太尼与芬太尼用于下肢骨折患者术后静脉镇痛的效果比较

Comparison of the effect of sufentanil and fentanyl for postoperative intravenous analgesia in patients with lower extremity fracture

目的:探讨舒芬太尼和芬太尼用于下肢骨折患者术后静脉镇痛的效果。方法:收治行硬膜外麻醉下肢骨折手术患者100例,平分两组,A1组使用舒芬太尼进行术后静脉镇痛;A2组使用芬太尼进行术后静脉镇痛,对比分析两组患者术后15、30 h的镇痛效果及不良反应发生率。结果:A1组术后15 h无痛率为92.00%,A2组为76.00%;A1组术后30 h无痛率为96.00%,A2组为78.00%;A1组均高于A2组,差异有统计学意义(P<0.05)。A1组不良反应发生率为6.00%,明显低于A2组的20.00%,差异有统计学意义(P<0.05)。结论:舒芬太尼用于术后静脉镇痛的效果较芬太尼明显,并且不良反应发生率较低。

Objective：To investigate the effect of sufentanil and fentanyl on postoperative intravenous analgesia in patients with fracture of the lower limbs.Methods：lO0 patients underwent epidural anesthesia for lower extremity fracture surgery were selected. They were divided into the two groups on average.The group AI used sufentanil for postoperative intravenous analgesia.The group A2 used fentanyl for postoperative intravenous analgesia.The analgesic effect and adverse reaction rate of 15 h and 30 h after operation in the two groups of patients were compared and analyzed.Results：In the group Al,the painless rate was 92.00% 15 h after operation and 76.00% in the group A2;in the group Al,the painless rate was 96.00% after 30 h operation;in the group A2,it was 78.00%.The A1 group was higher than the group A2,and the difference was statistically signifieant（P 〈 0.05）.The incidence of adverse reaction in the group A1 was 6% lower than that of the group A2 of 20% ,and the difference was statistically significant（P〈 0.05）.Conclusion：The effect of sufentanil for postoperative intravenous analgesia is more obvious than that of fentanyl,and the incidence of adverse reaction is low.