女性乳腺疼痛症患者血清甲状腺激素水平变化的临床意义

Clinical significance of changes in serum thyroid hormone levels in women with breast pain

目的:探讨女性乳腺疼痛症患者血清甲状腺激素水平变化的临床意义。方法:收治女性乳腺疼痛症患者120例为观察组,选取同期健康体检女性120例为对照组,两组均检测甲状腺过氧化物酶(TPO)、四碘甲状原氨酸(T_4)、三碘甲状腺原氨酸(T_3)、促甲状腺激素(TSH)等指标,比较检测结果。结果:乳腺疼痛同年龄有密切的关系,<45岁女性乳腺疼痛率明显高于≥45岁年龄段女性(P<0.05)。≥45岁的乳腺疼痛患者合并甲状腺疾病患者T_3水平明显高于无甲状腺疾患者,且与对照组相比,差异有统计学意义(P<0.05)。观察组患者中合并腺体紊乱者血清T_4水平明显高于无腺体紊乱者,观察组TPO、TG明显高于对照组(P<0.05)。结论:女性乳腺疼痛症与TPO、TG、T_4水平以及年龄有着直接的关系,可以通过以上指标对女性乳腺疼痛症的诊断提供参考依据。

Objective：To explore the clinical significance of changes in serum thyroid hormone levels in women with breast pain. Methods：120 female patients with breast pain were selected as the observation group,and 120 healthy women were selected as the control group.The two groups were detected for thyroid peroxidase（TPO）,tetraiodothyronine（T4）,triiodothyronine（T3）,thyroid stimulating hormone（TSH） and other indicators.We compared the detection results.Results：Breast pain was closely related to age, the breast pain rate in less than 45 years old female was significantly higher than that of more than 45 years old female（P 〈 0.05）. The T3 level in patients with breast pain and thyroid disease more than 45 years old was significantly higher than that of patients without thyroid disease,and the difference was statistically significant compared with the control group（P 〈 0.05）.In the observation group,the level of serum T4 in patients with disorder of glands was significantly higher than those with no glandular disorder,the TPO and TG of the observation group were significantly higher than the control group（P〈 0.05）.Conclusion：There was a direct relationship between female breast pain with TPO,TG,T4 and age.The above indicators can provide a reference for the diagnosis of female breast pain.