肠道微生物与过敏性疾病关系的研究进展

Research progress of relationship between intestinal microbiota and allergic diseases

过敏性疾病是当今世界性的重大卫生学问题。肠道菌群结构异常与过敏性疾病的发生、发展关系密切。生命早期肠道菌群结构的形成过程受到分娩方式、喂养方式、益生菌或益生元的添加、遗传等多种因素的影响,并且生命早期肠道菌群结构异常是其后期发生过敏性疾病的重要影响因素。本文拟结合最新文献,探讨早期肠道菌群结构异常与过敏性疾病发生、发展之间的关系。

Allergic diseases is a major worldwide health problem. The abnormal structure of intestinal microbiota is closely related to the occurrence and development of allergic diseases. The formation of intestinal microbiota in early life is influenced by many factors,such as the mode of delivery,feeding methods,the addition of probiotics or prebiotics,heredity and so on. The abnormal structure of intestinal microbiota in early life is an important factor influencing the occurrence of allergic diseases in the later life. In this paper,we will discuss the relationship between the abnormal structure of intestinal microbiota in early life and allergic diseases with the latest literature.