睫状肌麻痹剂对眼部组织的影响

Effect of cycloplegics on ocular tissue

睫状肌麻痹剂作为M胆碱能受体阻断剂，导致暂时性眼调节麻痹及瞳孔扩大，还出现角膜中央厚度、角膜容积增加，前房深度和前房容积增大，晶状体、睫状体、脉络膜变薄，高阶像差增大，屈光度改变等多方面的变化。并且有些变化在不同的年龄、性别、屈光类型及不同制剂间存在差异。睫状肌麻痹剂在眼科临床应用总体上是安全的，虽然其对眼部组织的影响是暂时性的，了解睫状肌麻痹前后眼部形态结构及生物参数的的变化，对临床的诊断、治疗工作将产生积极的影响。

Cycloplegics as M cholinergic receptor blocker, results temporarily in paralysis of accommodation and mydriasis, and also increases in central corneal thickness, corneal volume, anterior chamber depth and anterior chamber volume and higher-order aberrations. It can decrease the thickness of lens, ciliary body, choroid. It also makes diopter changes. There are some differences of those changes in different age, sex, type of refraction and different preparations. Cycloplegic agents in clinic are generally safe, although its effect on ocular tissue is temporary. To understand the changes of ocular morphology and biological parameters before and after cycloplegia will have a positive impact on the clinical diagnosis and treatment.