补肾通络方联合热敏药灸治疗仪对腰椎间盘突出症患者疗效及对炎症因子的影响

Effects of Bushentongluo recipe combined with thermosensitive moxibustion therapy apparatus on lumbar disc herniation and its influence on inflammatory factors

目的:探讨补肾通络方联合热敏药灸治疗仪对腰椎间盘突出症患者疗效及对炎症因子的影响。方法:将240例腰椎间盘突出症患者分为观察组和对照组,每组120例。对照组采用热敏药灸治疗仪治疗。观察组在对照组基础上,联合补肾通络方治疗。改良JOA脊柱功能评分(m-JOA评分)量表评定患者病情变化。采用视觉模拟评分法(VAS)评估患者疼痛程度。采用健康调查简表(SF-36评分)评估患者的生存质量。检测两组患者治疗前后C反应蛋白(CRP)、白介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)、白介素6(IL-6)的水平。结果:观察组比对照组的治疗效果更佳,差异有统计学意义(P<0.05);两组治疗后的mJOA评分、VAS评分较治疗前均明显降低,SF-36评分明显增高(P<0.05);治疗后,观察组的mJOA评分、VAS评分明显低于对照组,SF-36评分明显高于对照组,差异有统计学意义(P<0.05);两组治疗后的CRP、IL-1β、TNF-α、IL-6较治疗前均明显降低(P<0.05);治疗后,观察组的CRP、IL-1β、TNF-α、IL-6明显低于对照组,差异有统计学意义(P<0.05)。结论:补肾通络方联合热敏药灸治疗仪治疗腰椎间盘突出症的疗效确切,能显著减轻炎症反应。

AIM： To investigate the effects of Bushentongluo recipe combined with Moxibustion with thermosensitive herbs on lumbar disc herniation and its influence on inflammatory factors. METH-ODS： A total of 240 patients with lumbar disc herniation were divided into observation group and control group, 120 cases in each group. The control group was treated with thermosensitivc moxibustion combined with tetrandrine. The observation group was treated with Bushentongluo recipe on the basis of the control group. The modified JOA spine function score （m-JOA scale ） was used to assess the changes in the patient′s condition. Visual analogue scale （VAS） was used to assess the patient′s pain level. The quality of life was assessed by a health survey brief （SF-36 score ）. The levels of C-reactionprotein, interleukin-1β, tumor necrosis factor-α and interleukin-6 were detected before and after treatment in the two groups. RESULTS：The curative effect of the observation group was better than that of the control group. The difference was statistically significant （P〈0.05）. The m-JOA scores and VAS scores of the two groups were significantly lower than those before treatment, and the SF-36 score was significantly higher than those before treatment （P〈0.05）. After treatment, the m-JOA score and VAS score of the observation group were significantly lower than that of the control group, and the SF-36 score was significantly higher than that of the control group. The difference was statistically significant （P〈0.05）. The levels of CRP, IL-1β, TNF-α and IL-6 in the two groups were significantly lower those before treatment （P〈0.05 ）. After treatment, the CRP, IL-1β, TNF-α and IL-6 levels of the observation group were significantly lower than those of the control group. The difference was statistically significant （P〈0.05）. CONCLUSION： Bushentongluo recipe combined with Moxibustion with thermosensitive drugs is effective in treating lumbar disc herniation and can significantly reduce the inflammatory response.