托莫西汀治疗小儿注意缺陷多动障碍合并焦虑的疗效研究

Tomoxetine treatment of children with attention deficit hyperactivity disorder combined with anxiety

目的探究托莫西汀治疗小儿注意缺陷多动障碍合并焦虑的疗效。方法选取本院收治住院的小儿注意缺陷多动障碍(ADHD)合并焦虑的患儿82例为研究对象,依据患儿入院先后顺序分为传统组和治疗组,各41例,其中传统组给予哌甲酯进行治疗,实验组则给予盐酸托莫西汀进行治疗,观察各组患儿的治疗效果,并分析其安全性。结果实验组患儿的ADHD量表评分及其焦虑性情绪筛查量表评分(SCARED)均较传统组有所改善(P<0.05)。同时实验组患儿药物不良反应发生率远低于传统组(P<0.05)。结论针对ADHD患儿给予盐酸托莫西汀进行治疗,可改善患儿焦虑情绪、缓解多动或冲动行为症状,且药物不良反应较低,对疾病的治疗具有一定的安全性和可行性。

Objective To explore the efficacy of tomoxetine in the treatment of attention deficit hyperactivity disorder in children with anxiety.Methods Eighty-two children with attention deficit hyperactivity disorder（ADHD） combined with anxiety were enrolled in this hospital. According to the order of admission, the patients were divided into traditional group and treatment group, 41 cases in each group. The methyl ester was treated.The experimental group was treated with tomoxetine hydrochloride. The treatment effect of the children in each group was observed and the safety was analyzed. Results The ADHD scale and SCARED scores in the experimental group were improved compared with the traditional group（P〈0.05）. At the same time, the incidence of adverse drug reactions in the experimental group was much lower than in the traditional group（P〈0.05）.Conclusion The treatment of children with ADHD with tomoxetine hydrochloride can improve the anxiety of the children, relieve the symptoms of hyperactive or impulsive behaviors, and has low adverse drug reactions. It has certain safety and feasibility for the treatment of the disease.