骨科领域精准医疗的观念、特点及价值

Concepts, characteristics and values of precision medicine in the field of orthopedics

背景:精准医疗注重疾病的深度特征和治疗的高度精准性,是精确准时的个体化诊断治疗方式,近年来,逐渐成为医学界关注的热点。而作为一种全新的医学概念与医疗模式,其在骨科临床治疗中自身价值逐渐得到凸显。目的:总结目前精准医疗在骨科领域的研究现状及进展。方法:以"精准医疗,骨科,骨,3D打印,计算机辅助导航,微创,基因"为中文检索词,以"precision medicine,Orthopedics,bone,3D printing,computer assisted navigation,minimal invasive,gene"为英文检索词,在中国知网和Pub Med数据库检索近十余年国内外关于精准医疗在骨科领域应用的相关文献。结果与结论:(1)在骨科疾病的防治研究中,3D打印技术、计算机辅助导航技术、精准微创骨科技术、基因研究等技术正是实现精准化、个性化医疗的有效手段;(2)精准医疗这一新的医学模式的出现,丰富了骨科疾病的治疗手段,提高了治疗效果,给广大患者带来了新的曙光,给从事骨科疾病临床与基础研究的医学工作者、科研人员提供了新的思路和启发。

BACKGROUND： Precision medicine pays attention to the depth characteristics of the disease and the high precision of the treatment, and is a precise and accurate personalized approach of the diagnosis and treatment of the disease. In recent years, it has gradually become the hotspot of the medical field. As a new concept of medicine and medical model, its value in clinical treatment of orthopedics has been gradually highlighted. OBJECTIVE： To summarize the current status and progress of precision medicine in the field of orthopedics.METHODS： A computer-based search of PubMed and CNKI databases was performed for literatures about application and prospect of precision medicine in the field of orthopedics in and outside China published within the past 10 years using the keywords of ＂precision medicine, Orthopedics, bone, 3D printing, computer assisted navigation, minimal invasive, gene＂. RESULTS AND CONCLUSION： （1） In the study on the prevention and treatment of the disease of orthopedics, 3D printing technology, computer assisted navigation technology, precision minimally invasive orthopedic technology, and gene research are four effective way to achieve precise and personalized healthcare. （2） The appearance of precision medicine, a novel medicinal model, enriches the treatment of the disease in the field of orthopedics and enhances the curative efficacy of the disease. Precision medicine brings the new dawn to the patient and provides some new clues for medical workers and researchers engaged in the clinical and basic research of the disease in the field of orthopedics.