我国生物样本库运营规划现状

A Survey of Biobank Business Planning in China

目的评估我国生物样本库的运营规划现状。方法对国内63个主要生物样本库展开问卷调查。问卷内容包括生物样本库基本信息、运营规划、样本利用率、用户/客户群体、市场推广/广告、成本回收和业绩指标等6个类别,对6个类别的调查数据进行描述性分析。结果 63个生物样本库中,96.8%(61/63)属于学术机构或公立医院;19.0%(12/63)已有运营规划,39.7%(25/63)正在筹备运营规划,41.3%(26/63)尚无运营规划;85.0%(34/40)实际利用率低于20%,且97.5%(39/40)低于目标利用率;88.6%(1084/1223)的样本仅用于样本库或所属机构内部使用,不对外共享。结论本次调查结果初步反映,我国生物样本库运营规划情况不容乐观,样本实际利用率较低,且普遍低于其目标利用率,对外共享不足,未来应进一步加强国内生物样本库的合作和共享。

Objective This study aimed to gauge the current state of biobank business planning in China.Methods We conducted a survey among the directors or main participants of 63 biobanks in China. The questionnaire had six categories,including basic information about the biobanks,business planning,utilization,users/customers,marketing/advertising,and cost recovery/performance measures. In this report,we presented a descriptive analysis of the responses in the survey. Results In our survey,96. 8%（ 61/63） of the biobanks belonged to academic institutes or public hospitals; 19. 0%（ 12/63） had business plans; 39. 7%（ 25/63） had a business plan in progress; 41. 3%（ 26/63） had no business plan. In 85. 0%（ 34/40） of the biobanks,the actual utilization rate was less than 20%; and in 97. 5%（ 39/40） of the biobanks,the actual utilization rate of their bio-specimen collections was generally lower than the targeted one. About 88. 6%（ 1084/1223） samples were for internal use but not shared externally. Conclusions According to the results of this survey,the situationof biobank business planning in China is not so optimistic. The actual utilization rates of most biobanks were generally lower than their goals,and the main problem was lack of sharing. Cooperation and sharing of domestic biobanks should be further strengthened.