愈疡汤联合益君康灌肠治疗溃疡性结肠炎的临床观察

Effect of Ulcer-healing Decoction and Yijunkang enema on the treatment of ulcerative colitis

目的观察愈疡汤联合益君康灌肠对于溃疡性结肠炎的治疗效果。方法将20例门诊溃疡性结肠炎患者分试验组和对照组,试验组10例,采用愈疡汤联合益君康灌肠治疗;对照组10例,采取锡类散、地塞米松及庆大霉素联合灌肠治疗。分别记录2组治疗溃疡性结肠炎治疗前、治疗1、4周后,2组患者在外周血免疫球蛋白IgG、C3补体、血沉及C反应蛋白指数变化,以及患者在腹痛、腹泻、里急后重和脓血便等症状改善时间。结果 2组患者在外周血免疫球蛋白IgG、C3补体、血沉、C反应蛋白指标以及腹痛和脓血便改善时间差异有统计学意义(P<0.05);腹泻和里急后重改善时间上差异无统计学意义(P>0.05)。结论愈疡汤联合益君康灌肠对于溃疡性结肠炎具有较好的治疗效果。

Objective To observe the therapeutic effect of Ulcer-healing Decoction combined with Yijunkang enema on ulcerative colitis.Methods Twenty outpatients with ulcerative colitis were divided into experimental group and control group,and 10 patients in the experimental group were treated with Ulcer-healing Decoction combined with Yijunkang enema.The control group with 10 cases was given enema by sphindex,dexamethasone and gentamicin in combination.The changes of peripheral blood immunity protein IgG,C3 complement,erythrocyte sedimentation rate（ESR） and C-reactive protein in two groups before treatment,at 1 week,4 weeks after treatment were recorded,and the improvement time of abdominal pain,diarrhea,tenesmus feeling,stool with pus and blood and other symptoms were compared.Results There were significant differences in peripheral blood immunoglobulin IgG,C3 complement,ESR,C-reactive protein,and improvement time of abdominal pain and stool with pus and blood in two groups（P〈0.05）,but no differences were found in improvement time of diarrhea and tenesmus（P〉0.05）.Conclusion The combination of Ulcer-healing Decoction and Yijunkang enema has good effect on the treatment of ulcerative colitis.