轻链型心脏淀粉样变影像研究进展

Advances of imaging technology in diagnosis of light-chain cardiac amyloidosis

心脏淀粉样变指淀粉样物质沉积于心脏组织,轻链型心脏淀粉样变是最常见且预后最差的类型。因各种心脏淀粉样变的治疗手段不一致,早期、准确诊断心脏淀粉样变在临床中尤为关键。近年来,多种影像检查手段已应用于轻链型心脏淀粉样变的诊断。综述心脏MRI、超声及核素显像等技术在轻链型心脏淀粉样变中的研究进展。

Cardiac amyloidosis is characterized by extracellular amyloid deposition in heart tissue.Light-chain amyloidosis（AL） is the most common type of cardiac amyloidosis and associated with a worse survival than other types.Given that the prognosis and the treatment of this disease depend on the type of amyloidosis, an early accurate diagnosis is critical for the patients with cardiac amyloidosis. In recent years, medical imaging diagnostic techniques achieved major advances in diagnosis of AL. In this article, cardiovascular magnetic resonance imaging, advanced echocardiography and nuclear imaging in detecting of light-chain cardiac amyloidosis are reviewed.