2012～2017年重庆城市居民肺癌筛查结果分析

Results of Lung Cancer Screening Among Urban Residents in Chongqing,2012～2017

[目的]分析2012-2017年重庆城市居民肺癌筛查结果,为肺癌预防控制工作提供依据。[方法]动员重庆市沙坪坝区、南岸区、渝中区和九龙坡区40-74岁城市户籍居民自愿参加癌症危险因素调查和肺癌风险评估,并对评估出的肺癌高危人群提供免费的低剂量螺旋CT检查,分析城市肺癌的高危率、筛查率和检出率。[结果 ]5年完成问卷调查和高危人群评估207 961人,评估出肺癌高危人群41 183人（高危率19.80%,41183/207961）,低剂量螺旋CT检查15 278人（筛查率37.10%,15278/41183）,检出〈5mm实性/部分实性结节1500例（检出率9.82%,1500/15278）、〈8mm非实性结节473例（3.10%,473/15278）、阳性结节1973人（12.91%,1973/15278）、疑似肺癌243人（1.59%,243/15278）、随访成功且经病理诊断确诊为肺癌38例（0.25%,38/15278）、检出肺部其他疾病7332人次（47.99%,7332/15278）。[结论]有针对性地开展肺癌高危人群筛查,有利于及时发现居民肺部疾病,提高肺癌的早诊率、治疗率和生存率,对改善患者健康水平和生存质量具有重大意义。

[Purpose] To analyze the results of lung cancer screening among urban residents in Chongqing from 2012 to 2017. [Methods] Epidemiological investigation and lung cancer risk assessment were conducted among 40 ~74 years old urban residents in 4 districts（Shapingba,Nan＇an,Yuzhong and Jiulongpo） of Chongqing. Subjects with high risk of lung cancer received lowdose spiral CT for screening. The high risk rate,screening rate and detection rate of lung cancer were calculated. [Results] There were 207 961 residents who completed the questionnaires and lung cancer risk assessment during 5-year period. The 41 183 subjects were identified as high risk of lung cancer with a high risk rate of 19.80%. Total 15 278 subjects with high risk received low-dose spiral CT with a screening rate of 37.10%. Among 15 278 subjects there were 1500 cases of 5 mm solid/partial solid nodules（9.82%） and 473 cases of 8 mm non-solid nodules（3.10%）. The 1973 cases were diagnosed as positive nodules（12.91%） and 243 cases diagnosed as suspicious lung cancer（1.59%）;finally 38 cases were diagnosed as lung cancer by the pathology with a detection rate of 0.25%. Meanwhile,7332 cases were diagnosed as other lung diseases with a detection rate of 47.99%. [Conclusion] Screening of lung cancer among the high risk population would facilitate the early detection of lung cancer and other lung diseases,leading to improvement of the survival and quality of life of the patients.