影像组学在脑肿瘤精准诊疗中的应用和挑战

Radiomics in the precision diagnosis and treatment of brain tumor：the application and challenge

在强调“精准医学”的今天，对于患者和病理特异性的了解，是实施精准诊疗的关键。影像组学将提取自医学影像感兴趣区域的定量影像特征和肿瘤生物学和异质性等特征联系起来，是一种高通量定量分析方法。它提供了一种无创、便捷、动态和定量的方法了解患者的病理、基因等特异性信息。影像组学在脑肿瘤精准诊疗的应用前景巨大，可用于分子病理学诊断、定义肿瘤边界、预后和并发症的预测等，方便了对每个患者独特的疾病特征采取精确对应的预防、诊断、治疗和预后监控措施。

While emphasizing＂ Precision Medicine＂ nowadays, comprehending the specificity of patients and pathology is the key to achieving the precision diagnosis and treatment. Radiomics is a high- throughput quantitative analysis that combines the quantitative features from the region of interest on medical image and the biology and heterogeneity of tumor. It provides a non-invasive, convenient, dynamic, and quantitative method to collect the patient＇s specific features of pathology and gene. Radiomics holds promise for the precision diagnosis and treatment of brain tumor. It can be used for molecular pathology diagnosis, definition of tumor boundaries, prognosis, prediction of complications, and so on. It helps to develop individualized measures for the prevention, diagnosis, treatment, and prognostic monitoring based on their disease features.