布鲁氏菌病实验室常规检测方法研究进展

Progress of routine diagnosis for brucellosis in clinical lab

布鲁氏菌病（布病）是世界上七大易被忽视的人畜共患病之一，为我国法定乙类传染病。布病防控领域虽然取得了很大进展，但许多国家和地区人、畜间布病疫情仍然十分严峻。当前，布病诊断主要依靠病原学检测和血清学诊断，前者是布病诊断的＂金标准＂，但耗时较长且敏感性不高；后者是目前最常用的方法，主要包括试管凝集试验、补体结合试验、荧光偏振试验等。

Brucellosis is one of the seven most easily neglected zoonotic diseases around the world.It is classified as B infectious disease in China.Although great progress has been achieved in controlling the disease, brucellosis is still prevalent in some countries and regions among human and/or animals.Bacteriological testing and serological diagnosis are the major diagnostic methods of human brucellosis, the former is the ＂gold standard＂ , but time-consuming and less sensitive, and the latter is widely used for brucellosis diagnosis, including tube agglutination test, complement fixation test and fluorescence polarization test, etc.