儿童垂体柄阻断综合征的临床表现、影像学特点及治疗随访

Clinical and imaging characteristics and treatment follow - up of pituitary stalk interruption syndrome in children

垂体柄阻断综合征（PSIS）是一组严重影响儿童青少年生存质量、生长发育的内分泌临床症候群。由于其临床表现复杂多变，常被漏诊误治。现从PSIS的特征性临床表现及垂体磁共振成像特点入手，提出精确识别、诊断儿童PSIS的条件及依据，并对PSIS患儿激素替代治疗的方案步骤及随访重点提出建议。

Pituitary stalk interruption syndrome （PSIS） is associated with low viability and growth retardation of children and adolescents. Because of complex and variable clinical features, PSIS is often misdiagnosed. Now, the features of clinical manifestations and delineation of pituitary structure in magnetic resonance imaging are summarized, which can help the doctors to make more refined diagnosis, and to also make suggestions for hormone replacement thera- py and focus of follow - up.