摘要
液体活检已在恶性肿瘤研究领域取得重大进展,循环肿瘤细胞、循环肿瘤DNA、外泌体等可作为生物标志物用于上皮性卵巢癌的检测、动态监测病情变化、判断患者预后、评估化疗药物耐药性等,可为患者制定个体化的治疗方案提供依据,实现上皮性卵巢癌的精准医疗。
Liquid biopsies have made a great progress in malignant tumors research. Circulating tumor cells, circulating tumor DNA and exosomes can be regarded as biomarkers to he applied in diagnosis of epithelial ovarian cancer, monitoring progress dynamically, estimating prognosis and drug resistance in chemo- therapy, which can help doctors provide patients with individual treatment to realize precision medicine in epithelial ovarian cancer.
作者
唐慧芸
莫小雨
白莉平
郑艾
Tang Huiyun, Mo Xiaoyu, Bai Liping, Zheng Ai(Department of Obsterics and Gynecology, West China Second Hospital, Sichuang University; Key Laboratory of Birth Defects and Related Disease of Women and Children (Sichuan University) , Ministry of Education, Chengdu 610041, China)
出处
《国际肿瘤学杂志》
CAS
2018年第2期122-125,共4页
Journal of International Oncology
关键词
卵巢肿瘤
液体活检
Ovarian neoplasms
Liquid biopsy