梅毒抗体反应性献血者筛查方案和归队策略研究

Study on screening program and reentry strategy of syphilis antibody donors

目的优化梅毒螺旋体抗体(Anti-TP)筛查方案,制定Anti-TP反应性献血者屏蔽、归队策略。方法收集甘肃省红十字血液中心2016年5月-2017年5月ELISA筛查Anti-TP反应性标本249份,经TPPA法确证以及3个月后追踪检测,鉴别这些献血者Anti-TP是否为真(假)阳性,确定其归队还是继续屏蔽。结果 249份Anti-TP反应性标本中,TPPA确证阳性89份,不确定16份,此105名献血者作暂时性屏蔽;阴性144份,这部分献血者可以归队。任1种ELISA反应性标本中有2份为TPPA阳性,其S/CO值均≥1。符合归队的献血者追踪到61人,TPPA均为阴性。结论成功建立、完善了一个适合兰州地区初筛Anti-TP ELISA反应性献血者的筛查方案和归队流程。

Objective To establish blood donor deferral and reentry strategy by optimizing anti-TP screening programs.Methods All 249 samples screened reactive for Anti-TP by ELISA were collected from May 2016 to May 2017,and then after confirmation by TPPA and tracking after 3 months,donors were identified as either true positive or false positive,so as to determine to be reenterred or deferred temporarily. Results Of the 249 Anti-TP-responsive specimens,89 were positive for TPPA,16 were indeterminate,and the 105 blood donors were temporarily shielded; 144 were negative and the blood donors could return. Two of the ELISA-responsive specimens were positive for TPPA and had S/CO values greater than one. The eligible donors tracked 61 people,and TPPA was negative. Conclusion A screening program and a return process for the screening of Anti-TP ELISA reactive blood donors in Lanzhou were successfully established and improved.