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经鼻无创间歇正压通气治疗早产儿呼吸窘迫综合征疗效评价 被引量:2

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摘要 目的探讨分析经鼻无创间歇正压通气(NIPPV)治疗早产儿呼吸窘迫综合征的临床疗效。方法选取2014年3月—2017年8月本院新生儿科收治的70例呼吸窘迫综合征早产儿随机分为A组和B组,A组给予经鼻间歇正压通气治疗,B组给予经鼻持续气道正压通气(NCPAP)治疗,比较两组患儿治疗前、治疗后12 h血气分析、氧合功能情况、呼吸指数、成功率、病死率、辅助通气时间、并发症发生情况。结果治疗前两组患儿Pa O2、Pa CO2、P/F、RI指标水平差异无统计学意义(P>0.05),治疗后12 h两组患儿Pa O2、RI显著提高,Pa CO2、P/F显著降低,且A组患儿Pa O2、Pa CO2、P/F、RI指标改善程度更显著,A、B组患儿治疗成功率分别为88.57%、65.71%,A组患儿治疗成功率较B组显著提高,差异具有统计学意义(P<0.05),A、B组患儿病死率分别为0.00、2.86%,两组患儿病死率差异无统计学意义(P>0.05),A组患儿辅助通气时间较B组患者显著缩短,A组患儿腹胀、CO2潴留发生率较B组患儿显著降低,差异均具有统计学意义(P<0.05),两组患儿肺漏气、鼻损伤、颅内出血发生率差异无统计学意义(P>0.05)。结论经鼻无创间歇正压通气治疗早产儿呼吸窘迫综合征可显著提高治疗的成功率,降低病死率和并发症发生率,缩短辅助通气时间,改善患儿呼吸困难症状,值得在临床上广泛推广。
作者 张宇茂 陈健
出处 《泰山医学院学报》 CAS 2018年第5期554-556,共3页 Journal of Taishan Medical College
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