拜阿司匹林肠溶片与阿司匹林肠溶片治疗短暂性脑缺血发作的效果观察

Effect of Aspirin Enteric-coated Tablets Versus Aspirin Enteric-coated Tablets in Treating Transient Ischemic Attack

目的:探究拜阿司匹林肠溶片治疗短暂性脑缺血发作临床效果。方法:选取2015年6月-2017年3月笔者所在医院收治的短暂性脑缺血发作的患者88例,随机将其分为两组。参照组采用阿司匹林肠溶片+波立维治疗,研究组采用拜阿司匹林肠溶片+波立维治疗,比较两组患者的治疗效果及出血风险。结果:研究组患者治疗后血小板(PTL)与参照组比较,差异无统计学意义(t=0.268,P>0.05);血浆纤维蛋白原(FIB)低于参照组,凝血酶原时间(PT)和活化部分凝血活酶时间(APTT)均长于参照组,差异均有统计学意义(t=9.409、3.387、5.157,P<0.05)。研究组患者的治疗有效率为93.2%,高于参照组的77.3%,差异有统计学意义(X^2=4.422 6,P<0.05)。结论:拜阿司匹林肠溶片可提高短暂性脑缺血发作患者的治疗有效率,具有很高的应用价值。

Objective：To investigate the clinical effect of Bayaspirin Enteric-coated Tablets in treating transient ischemic attack.Method：A total of 88 patients with transient ischemic attack in our hospital from June 2015 to March 2017 were selected and randomly divided into two groups.The reference group was treated with Aspirin Enteric-coated Tablets combined Clopidogrel Hydrogen Sulfate,the study group was treated with Bayaspirin Enteric-coated Tablets combined Clopidogrel Hydrogen Sulfate.The two groups were compared with the therapeutic effect and risk of bleeding.Result：The platelet（PTL） of the study group had no difference compared with the reference group（t=0.268,P〉0.05）,and the plasma fibrinogen（FIB） was lower than that of the reference group;the prothrombin time（PT） and the activated partial thromboplastin time（APTT） were all longer than those in the reference group,the differences were statistically significant（t=9.409,3.387,5.157,P〈0.05）.The effective rate of the study group was 93.2%,which was higher than 77.3% of the reference group,and the difference was statistically significant（ X2=4.422 6,P〈0.05）.Conclusion：Bayaspirin Enteric-coated Tablets can improve the effective rate of transient ischemic attack patients,and has high application value.