摘要
随着人口老龄化的进程,心血管疾病患者数量逐渐增加,慢性心力衰竭作为各种心血管疾病发展的最后阶段,严重影响着患者的生活质量,甚至威胁生命。研究发现,心力衰竭和炎性因子之间的联系密切,其中促炎性因子对疾病的发展起着促进作用,抗炎性因子则对疾病的发展起着抑制作用。现对近年来炎性因子在心力衰竭中作用机制的发现进行了整理,以期对完善临床慢性心力衰竭的诊断、治疗和预后策略有所帮助。
With the population aging process,a gradual increase in the number of patients with cardiovascular disease,chronic heart failure as the last stage of a variety of cardiovascular disease,seriously affects the quality of life of patients,and even life-threatening. The study found that there is a close relationship between heart failure and inflammatory factors, in which proinflammatory factors play roles in promoting the development of disease, and anti-inflammatory factors play inhibitory roles in the development of the disease. In this paper, the mechanism of inflammatory factors in heart failure in recent years has been sorted out,in order to improve the diagnosis, treatment and prognosis strategy of clinical chronic heart failure.
作者
刘兆杰
杨娟
李文茜
苑素云
LIU Zhaojie;YANG Juan;LI Wenqian;YUAN Suyun(Graduate School,Shanghai University of Traditional,200032,China;Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)
出处
《心血管病学进展》
CAS
2018年第3期388-391,共4页
Advances in Cardiovascular Diseases
基金
国家自然科学基金项目(81328025)
上海市自然科学基金项目(12ZR1432200)
国家中医临床研究基地业务建设科研专项(JDZX2012114)
关键词
心力衰竭
炎性因子
免疫
Heart failure
Inflammatory factors
Immune