期刊文献+

血浆OX40L水平对ST段抬高型心肌梗死患者PCI术后发生MACE的预测价值 被引量:6

下载PDF
导出
摘要 目的探讨血浆OX40L水平对ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)术后发生心脏不良事件(MACE)的预测价值。方法选取接受PCI治疗的STEMI患者100例,检测术前、术后即刻、24h、48 h及72 h血浆OX40L水平变化;术后随访1年,统计患者主要MACE及再入院率;根据是否发生MACE分为MACE组、无MACE组,比较两组一般资料,并分析PCI术后发生MACE与血浆OX40L水平相关性及其危险因素。结果患者术后即刻、24 h、48 h及72 h血浆OX40L水平均高于术前(P均<0.05);100例患者均获随访,MACE发生率为22.00%,再入院率为21.00%;MACE组吸烟、糖尿病比例、OX40L峰值均高于无MACE组,LDL-C低于无MACE组(P均<0.05);多因素Logistic回归分析结果显示,糖尿病、LDL-C及OX40L水平是PCI治疗后STEMI患者MACE发生的重要危险因素(P均<0.05)。结论血浆OX40L表达在STEMI患者PCI术后增高,OX40L可作为预测STEMI患者PCI术后MACE的生物因子。
出处 《山东医药》 CAS 2018年第17期52-54,共3页 Shandong Medical Journal
基金 阜阳市2014年卫计委科研项目(201437)
  • 相关文献

参考文献12

二级参考文献82

  • 1丁嵩,何奔.急性心肌梗死心肌血流再灌注评价技术[J].介入放射学杂志,2006,15(4):250-253. 被引量:6
  • 2Collaborative Research Group of Reperfusion Therapy in Acute Myocardial Infarction.重组葡激酶与重组组织型纤溶酶原激活剂治疗急性心肌梗死的随机多中心临床试验[J].中华心血管病杂志,2007,35(8):691-696. 被引量:43
  • 3Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery ( EACTS ), European Association for Percutaneous Cardiovascular Interventions (EAPCI), Wijns W, et al. Guidelines on myocardial revascularization. Eur Heart J,2010 , 31:2501-2555.
  • 4Levine GN, Bates ER, Blankenship JC, et al. 2011 ACCF/AHA/ SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the society for cardiovascular angiography and interventions. Circulation, 2011, 124 :e574-651.
  • 5Hillis LD, Smith PK, Anderson JL, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery. A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, developed in collaboration with the American Association for Thoracic Surgery, Society of Cardiovascular Anesthesiologists, and Society of Thoracic Surgeons. J Am Coil Cardiol, 2011,58 :e123-210.
  • 6Nashef SA, Roques F, Michel P, et al. European system for cardiac operative risk evaluation ( EuroSCORE ). Eur J Cardiothorac Surg, 1999,16:9-13.
  • 7Serruys PW, Morice MC, Kappetein AP, et al. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med, 2009,360:961- 972.
  • 8Peterson ED, Dai D, DeLong ER, et al. Contemporary mortality risk prediction for percutaneous coronary intervention: results from 588,398 procedures in the National Cardiovascular Data Registry. J Am Coil Cardiol,2010,55:1923-1932.
  • 9Online STS fish calculator [ S/OL]. [ 2012-01-01 ]. http:// riskcalc, sts. org/STSWebRiskCalc273/de, aspx.
  • 10Mehta SR, Tanguay JF, Eikelboom JW, et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes ( CURRENT-OASIS 7 ): a randomised factorial trial. Lancet,2010,376 : 1233-1243.

共引文献2844

同被引文献68

引证文献6

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部