摘要
Background Postoperative death of thoracic endovascular aortic repair （TEVAR） occurred in patients with type B aortic dissection （TBAD）. The prognostic value of anemia, an important problem during the perioperative period, is unknown. Methods According to predefined criteria, 184 TBAD patients underwent TEVAR were di-vided into two groups： non-anemia group and anemia group. Clinical data were compared between groups and multiple Cox proportional hazard regression analyses were performed to detect the risk factors of long-term mor-tality. Results After median 2.5 years follow-up, 21 patients died. Long-term mortality was significant higher in patients with anemia （23.9% vs. 8.1%, P=0.006）. Multivariate analyses showed that anemia was independently associated with increased risk of long-term mortality （HR=3.21, 95% CI： 1.31-7.89, P=0.011）. The ROC curve showed that hemoglobin level had predictive role for long-term mortality （AUC=0.742, P〈0.001）. The optimal cut-off was 130.2g/L, with sensitivity and specificity being 85.7% and 52.0%, respectively. Conclusions Admission anemia was independently associated with increased risk of long-term post-TEAVR mortality in TBAD pa-tients. Pre-TEAVR hemoglobin measure could be a risk assessment tool for TBAD patients undergoing TEAVR.
Background Postoperative death of thoracic endovascular aortic repair （TEVAR） occurred in patients with type B aortic dissection （TBAD）. The prognostic value of anemia, an important problem during the perioperative period, is unknown. Methods According to predefined criteria, 184 TBAD patients underwent TEVAR were di-vided into two groups： non-anemia group and anemia group. Clinical data were compared between groups and multiple Cox proportional hazard regression analyses were performed to detect the risk factors of long-term mor-tality. Results After median 2.5 years follow-up, 21 patients died. Long-term mortality was significant higher in patients with anemia （23.9% vs. 8.1%, P=0.006）. Multivariate analyses showed that anemia was independently associated with increased risk of long-term mortality （HR=3.21, 95% CI： 1.31-7.89, P=0.011）. The ROC curve showed that hemoglobin level had predictive role for long-term mortality （AUC=0.742, P〈0.001）. The optimal cut-off was 130.2g/L, with sensitivity and specificity being 85.7% and 52.0%, respectively. Conclusions Admission anemia was independently associated with increased risk of long-term post-TEAVR mortality in TBAD pa-tients. Pre-TEAVR hemoglobin measure could be a risk assessment tool for TBAD patients undergoing TEAVR.
