摘要
The paper designed a bionic woven tracheal stent and the stent was a multi-layer tubular structure with a transverse pipeline.Polydioxanone( PDO) monofilament and β-hydroxybutyrate and β-hydroxyvalerate copolymers/polylactic( PHBV/PLA) multifilament were chosen as the tissue engineering tracheal stent materials,and chitosan was chosen as the coating material. This study selected appropriate basic fabric structures and prepared the tracheal stent by setting reasonable weaving parameters,then treated the sample with coating and heat setting. Radical compression performances of the horizontal pipeline and longitudinal pipeline of this tracheal stent were investigated,and the experimental results showed that the stent had good performance on radial supporting force and elastic recovery,which meant it could supply adequate supports for cell growth and tissue regeneration of tracheal lesions; the horizontal pipeline could provide a good experimental foundation for reconstruction of the cartilage ring.
The paper designed a bionic woven tracheal stent and the stent was a multi-layer tubular structure with a transverse pipeline.Polydioxanone（ PDO） monofilament and β-hydroxybutyrate and β-hydroxyvalerate copolymers/polylactic（ PHBV/PLA） multifilament were chosen as the tissue engineering tracheal stent materials,and chitosan was chosen as the coating material. This study selected appropriate basic fabric structures and prepared the tracheal stent by setting reasonable weaving parameters,then treated the sample with coating and heat setting. Radical compression performances of the horizontal pipeline and longitudinal pipeline of this tracheal stent were investigated,and the experimental results showed that the stent had good performance on radial supporting force and elastic recovery,which meant it could supply adequate supports for cell growth and tissue regeneration of tracheal lesions; the horizontal pipeline could provide a good experimental foundation for reconstruction of the cartilage ring.
作者
WANG Liping
LI Yuling
MA Yanxue
王利平;李毓陵;马颜雪(Key Laboratory of Textile Science and Technology,Ministry of Education,College of Textiles,Donghua University)
基金
Biomedical Textile Materials Science and Technology(111 Project),China(No.B07024)
National Natural Science Foundation of China(No.H0106)
Shanghai Pujiang Program,China(No.2015PJC0002)
