外耳道腺样囊性癌临床病理分析及文献复习

Clinicopathological analysis and literature review of adenoid cystic carcinoma of the external auditory canal

目的:探讨外耳道腺样囊性癌的临床病理特点,提高对该病的认识。方法:观察6例外耳道腺样囊性癌的组织学特点及免疫组化特性。结果:患者男性3例,女性3例,年龄41~68岁,平均年龄55岁,6例均有耳部疼痛,2例发生肺转移。肿物最大径0.8~4 cm,实性,无包膜,镜下均以筛状结构为主,伴有不同比例的管状和实性结构,4例见神经浸润,免疫组化CK和p63均阳性。结论:外耳道腺样囊性癌较少见,易发生肺转移,诊断靠病理诊断。

Objective： To study the clinicopathological features of adenoid cystic carcinoma of the external auditory canal and to improve the understanding of the disease. Methods： To observe the histological features and immunohistochemical characteristics of 6 cases of adenoid cystic carcinoma of the external auditory canal. Results： There were 3 males and 3 females,aged 41~68 years,with an average age of 55 years,6 patients had ear pain,2 cases had lung metastasis.The maximum diameter of tumor was 0.8~4 cm,solid and no capsule.All the cases were mainly cribriform,with different proportions of tubular and solid,4 cases showed perineural invasion,and immunohistochemical CK and p63 were all positive. Conclusion： Adenoid cystic carcinoma of the external auditory canal is rare and prone to pulmonary metastasis,and the diagnosis is based on pathological diagnosis.