登革热检测技术应用及发展

Application and development of dengue fever detection

登革热是由登革病毒引起的传染性疾病,长期以来在世界范围特别是热带和亚热带地区广泛流行。早期实验室诊断是登革热疫情防控的关键手段之一。随着医学发展,登革热的诊治日趋成熟,不同的诊断方法存在着不同的优点和缺点。近年来,病毒分离、免疫学检测、分子生物学诊断方面的研究取得较大进展,本文就近年登革病毒早期快速检测技术进展及不同方法选用时机作一综述,并就将来可能的重点研究方向进行展望,以期作为登革热防控和研究的实用参考。

Dengue fever is an infectious disease caused by dengue virus and has long been widespread in the world,especially in tropical and subtropical regions. Early laboratory diagnosis is one of the key means to prevent and control dengue fever. With the development of medicine,the diagnosis and detection of dengue fever are improved. However, different diagnostic methods have different advantages and disadvantages. In recent years,great progress has been made in the research of virus isolation,immunological detection and molecular biology diagnosis. In this review,the rapid detection technology of dengue virus and the application of different methods for dengue fever diagnosis will be discussed,in order to serve as a practical reference for the control and research of dengue fever.