炙甘草汤联合酒石酸美托洛尔片治疗风心病心力衰竭并房颤的临床疗效

Efficacy of the Zhigancao decoction and metoprolol tartrate tablet on rheumatic heart disease with heart failure and atrial fibrillation

目的:观察炙甘草汤联合酒石酸美托洛尔片治疗风心病心力衰竭并房颤的临床疗效。方法:选取在我院治疗的风心病心力衰竭并房颤患者86例(2014年10月-2016年10月期间)作为本研究中的观察对象。采用单双号分组法,将所有患者分为对照组与实验组,每组患者43例。其中对照组风心病心力衰竭并房颤患者给予单一使用酒石酸美托洛尔片治疗,实验组风心病心力衰竭并房颤患者采用炙甘草汤联合酒石酸美托洛尔片进行治疗。将两组患者的治疗总有效率、治疗前后的心功能指标[左室收缩末内径(LVESD)、左室舒张末内径(LVEDD)、左心射血分数(LVEF)及心率(HR)]变化进行对比分析。结果:实验组风心病心力衰竭并房颤患者的总有效率为95.35%,较对照组更优,P<0.05;治疗后,两组患者的心功能均较治疗前改善,且实验组改善程度较对照组更佳,P<0.05。结论:炙甘草汤联合酒石酸美托洛尔片治疗风心病心力衰竭并房颤患者的效果更为可观,可改善患者的心功能,值得进一步推广应用。

Objective： To observe the clinical efficacy of the Zhigancao decoction（ 炙甘草汤） and metoprolol tartrate tablet on rheumatic heart disease with heart failure and atrial fibrillation. Methods： 86 cases were divided into the control group and experimental group, 43 cases in each. The control group was treated with metoprolol tartrate tablets. The experimental group was treated with the Zhigancao decoction more. The total efficiency and cardiac function index（LVESD, LVEDD, LVEF and HR） were compared. Results： The total efficiency was 95.35% in experimental group and better than the control group, P〈0.05. After treatment, cardiac function was improved in groups. The improvement degree in the experimental group was better than the control group, P〈0.05. Conclusion： The Zhigancao decoction and metoprolol tartrate tablet is more significant, can improve heart function, and is worthy of further popularization.