浅析辛伐他汀联合抗栓治疗在脑梗死中的治疗价值

The value of simvastatin combined with antithrombotic therapy in the treatment of cerebral infarction

目的:分析研究辛伐他汀联合抗栓药物在治疗脑梗死中的作用。方法:利用随机数字表法,将入院的脑梗死患者分为两组,观察组各51例,在常规治疗的基础上给予辛伐他汀进行治疗;对照组51例,采用常规的治疗方法。记录两组脑梗死患者的治疗总有效率、血脂指标及炎性因子的水平。结果:在接受治疗后,观察组患者治疗的总有效率(90.20%)显著高于对照组(74.51%)(P<0.05);观察组患者的TC水平(4.45±1.46)及TG水平(1.07±0.36)显著低于对照组的TC水平(5.12±1.58)和TG水平(2.36±0.45)(P<0.05);观察组的炎性因子水平(6.43±3.27)明显比对照组(9.55±2.87)(P<0.05)低。结论:给予患者常规治疗基础上加入辛伐他汀和抗栓药物的联合治疗,能有效提升患者治疗的总有效率,帮助患者有效降低血脂水平和炎性因子水平,有利于患者身心康复,具有较显著的临床作用,值得推广。

Objective： To analyze the value of simvastatin combined with antithrombotic therapy in the treatment of cerebral infarction. Methods： Patients with cerebral infarction were divided into two groups by random number table method. 51 patients in the observation group were treated with simvastatin on the basis of routine treatment. In the control group, 51 cases were treated with routine therapy. The total effective rate, blood lipid index and inflammatory factor level were recorded in the two groups of patients with cerebral infarction. Results： After treatment, the total effective rate of the observation group was 90.20%, which was significantly higher than that in the control group, 74.51%,（P〈0.05）; The TC level（4.45±1.46） and TG level（1.07±0.36） in the observation group were significantly lower than that in the control group（5.12±0.58） and（2.36±0.45） respectively（P〈0.05）; The level of inflammatory factors in the observation group（6.43±3.27） was significantly lower than that in the control group（9.55±2.87）（P〈0.05）. Conclusion： Based on routine treatment, simvastatin combined with antithrombotic drugs could effectively improve the treatment efficiency, help patients reduce blood lipid levels and inflammatory factor levels effectively, which was conducive to physical and mental health of patients, it had significant value and was worthy of promotion.