超声电导仪佐治初治涂阳老年肺结核疗效分析

Analysis of Curative Effect of Ultrasound Conductivity Meter in Adjunctive Treatment of New Smear Positive Pulmonary Tuberculosis Patients

目的观察超声电导仪经皮透药治疗初治老年肺结核的疗效。方法选取2016年1—12月初治涂阳老年肺结核患者68例,将其随机分为观察组34例和对照组34例。观察组采用超声电导仪联合全身化疗,对照组仅采用全身化疗,两组均采用相同的化疗方案。观察记录两组患者在治疗前与治疗后2、3、6个月时痰结核菌转阴率、胸部X线病灶吸收率及不良反应等。结果观察组患者在2、3、6个月结束时痰检结果转阴率为46.7%(χ~2=4.91),67.7%(χ~2=10.39),86.7%(χ~2=12.53),均高于同时期对照组,差异有统计学意义(P<0.05)。观察组患者在2、3、6个月结束时病变吸收率为50.0%(χ~2=4.85),73.3%(χ~2=7.92),86.6%(χ~2=6.11),均高于同时期对照组,差异有统计学意义(P<0.05)。在不良反应方面,两组比较差异无统计学意义(P>0.05)。结论超声电导仪经皮局部透药辅助治疗初治涂阳老肺结核在痰菌转阴方面、病灶吸收方面疗效显著,且无严重不良反应。

Objective To observe the curative effect of transdermal drug delivery of ultrasound conductivity meter in adjunctive treatment of new smear positive pulmonary tuberculosis patients. Methods 68 cases of new smear positive pulmonary tuberculosis patients in our hospital from January to December 2016 were selected and randomly divided into two groups with 34 cases in each, the observation group used the ultrasound conductivity meter combined with general chemotherapy, while the control group were only treated with general chemotherapy, both groups used the same chemotherapy plan, and the negative rate of sputum tuberculosis, absorbility rate of chest X ray lesion and adverse reactions before treatment and in 2 months, 3 months and 6 months after treatment of the two groups were observed and recorded. Results The negative rate of sputum tuberculosis at the end of two months, three months and six months in the observation group were respectively 46.7%（χ^2=4.91）,67.7%（χ^2=10.39）,86.7%（χ^2=12.53）, which were higher than those in the control group at the same period, and the differences were statistically significant（P 0.05）,and the absorbility rate of lesions at the end of two months, three months and six months in the observation group were respectively 50.0%（χ^2=4.85）,73.3%（χ^2=7.92）,86.6%（χ^2=6.11）, which were higher than those in the control group at the same period, and the differences were statistically significant（P〈0.05）, and the difference in the adverse reaction between the two groups was not statistically significant（P〈0.05）. Conclusion The curative effect of ultrasound conductivity meter in adjunctive treatment of new smear positive pulmonary tuberculosis patients is obvious in improving the negative rate of sputum tuberculosis and lesion absobility, without severe adverse reactions.