泮托拉唑联合左氧氟沙星、阿莫西林治疗消化性溃疡的临床分析

Clinical Analysis of Pantoprazole, Levofloxacin and Amoxicillin in Treatment of Peptic Ulcer

目的探讨泮托拉唑联合左氧氟沙星、阿莫西林治疗消化性溃疡的临床效果。方法选择该院自2015年12月—2016年12月确诊的消化性溃疡患者资料120例,将所有患者平均分为两组,分别命名为观察组、对照组。每组例数均为60例。对照组给予奥美拉唑、克拉霉素、甲硝唑三种药物的联合治疗,观察组给予泮托拉唑联合左氧氟沙星、阿莫西林治疗的治疗形式。一段时间的治疗结束后,观察患者反应情况。结果两组患者无论是在治疗的总有效率上还是幽门螺杆菌的根除率上,均显示出观察组的治疗情况对比对照组更加优良。观察组的总有效率为95.00%,高于对照组的88.33%。观察组的患者阴性率为96.67%,高于对照组的80.00%。两组比较差异无统计学意义(P>0.05)。结论采用泮托拉唑联合左氧氟沙星、阿莫西林的治疗方式能够有效的改善消化性溃疡患者的身体情况,建议临床上广泛采用这种方式治疗患者。

Objective To study the clinical effect of pantoprazole, levofloxacin and amoxicillin in treatment of peptic ulcer. Methods 120 cases of patients with peptic ulcer diagnosed in our hospital from December 2015 to December2016 were selected and divided into two groups with 60 cases in each, the control group were treated with omeprazole,clarithromycin and metronidazole, while the observation group were treated with pantoprazole combined with levofloxacin and amoxicillin, after a period of time, the reactions of patients were observed. Results The total treatment effective rate and eradiation rate of helicobacter pylori in the observation group were better than those in the control group, and the total treatment effective rate in the observation group was higher than that in the control group,（95.00%vs 88.33%）, and the negative rate in the observation group was higher than that in the control group,（96.67% vs80.00%）, and the difference between groups was statistically significant（P〉0.05）. Conclusion The pantoprazole combined with levofloxacin and amoxicillin can effectively improve the physical conditions of patients with peptic ulcer,and it is suggested to be widely used in patients.