急性缺血性脑卒中阿替普酶静脉溶栓治疗临床观察

Clinical observation of intravenous thrombolysis with alteplase in the treatment of acute ischemic stroke

目的研究阿替普酶静脉溶栓治疗急性缺血性脑卒中的临床疗效。方法 96例急性缺血性脑卒中患者作为研究对象,按照治疗方式不同分为研究组与参照组,各48例。参照组采用常规治疗,研究组在常规治疗的基础上采用阿替普酶静脉溶栓治疗,比较两组患者的临床疗效。结果参照组显效17例、有效21例、无效10例,总有效率为79.17%(38/48);研究组显效28例、有效19例、无效1例,总有效率为97.92%(47/48);研究组患者总有效率显著高于参照组,差异具有统计学意义(P<0.05)。结论在急性缺血性脑卒中的临床治疗中加强应用阿替普酶静脉溶栓治疗,能够进一步提高患者的临床治疗效果,改善患者临床症状,值得推广。

Objective To study the clinical efficacy of intravenous thrombolysis with alteplase in the treatment of acute ischemic stroke. Methods A total of 96 acute ischemic stroke patients as study subjects were divided by different treatment Methods into research group and control group, with 48 cases in each group. The control group received conventional therapy, and the research group received intravenous thrombolysis with alteplase on the basis of conventional therapy. The clinical efficacy in two groups was compared. Results The control group had 17 excellent cases, 21 effective cases, and 10 ineffective cases, with total effective rate as 79.17%（38/48）, while the research group had 28 excellent cases, 19 effective cases, and 1 ineffective case, with total effective rate as 97.92%（47/48）. The research group had obviously higher total effective rate than the control group, and the difference was statistically significant（P〈0.05）. Conclusion Intensive application of intravenous thrombolysis with alteplase in the clinical treatment of acute ischemic stroke can further improve the clinical treatment effect of patients and improve their clinical symptoms. It is worth promoting.